Particulate solid reactants were mixed at liquidtosolid weight ratios of 0. Mechanical properties of hydroxyapatite single crystals from nanoindentation data a. Incorporation of nanoalumina improves mechanical properties. Xray diffraction xrd, fourier transform infrared spectroscopy ftir, xray fluorescence xrf. The effect of titanium oxide and hydroxyapatite on the mechanical properties of wollastonite d. Hydroxyapatite hap was studied from a first principle approach using the local density approximation lda method in aimpro code, in combination with various quantum mechanical qm and molecular mechanical mm methods from hypemchem 7. Roeder department of aerospace and mechanical engineering, the university of notre dame, notre dame, in 46556, usa received 25 july 2006. Gautam a, sunil kumar a, santoshkumar biradar b, sujin jose c and vijay kumar mishra d a advanced glass and glass ceramic research laboratory, department of physics, university of lucknow, lucknow226007, uttar pradesh, india. Application of ha to bone restoration and implants is especially important, and attracts much research interest. Comparison of physicalchemical and mechanical properties of. Based on animal experiments, mechanical properties of rabbit radii after grafting artificial gaps with a coralline hydroxyapatite ch material are discussed. Mechanical properties and biocompatibility of a biomaterial. Homogeneously dispersed composites of hydroxyapatite. The hybrid composites possess mechanical properties that are superior to most of the hapla composites in previous research while maintaining the biodegradability.
A computational approach has been presented to extract the elasticplastic properties of hydroxyapatite single crystals from nanoindentation data. Mechanical behavior of hydroxyapatite biomaterials. Hydrogelplga delivery system prolongs 2methoxyestradiolmediated antitumor effects in osteosarcoma cells. Mechanical properties of hydroxyapatite single crystals from. Influence of firing time on micromechanical properties of glass based coating on ti6al4v for biomedical applications. The method was validated by comparing its predictions to data obtained from literature. The biocompatibility, biodegradability and bioactivity make it extensively useful in interdisciplinary. Hydroxyapatite properties, uses and applications fluidinova. A study on mechanical properties of pmmahydroxyapatite nanocomposite. This study is focused on the role of nano hydroxyapatite particles on the mechanical properties of pmma ha nanocomposites. Hydrogelplga delivery system prolongs 2methoxyestradiolmediated antitumor effects in osteosarcoma cells next article in issue. Mechanical properties of hydroxyapatite composites. Mechanical properties of hydroxyapatite formed at physiological. Due to its outstanding properties such as biocompatibility, bioactivity, osteoconductivity and non toxicity and non inflammatory nature, nano hydroxyapatite bioceramic has got a variety of applications in medical and oral care areas.
In order to achieve a proper and homogeneous distribution of. Bioceramics, such as ha and fa, have been recognized as restorative materials e. Mechanical properties and cytocompatibility of biomimetic hydroxyapatitegelatin nanocomposites volume 21 issue 12 chingchang ko, michelle oyen, alison m. Mechanical properties of ceramic biomaterials 19,2527. The eect of the ph values and sintering temperatures on the physical, structural and mechanical properties of nano hydroxyapatite. Department of materials science and metallurgical engineering, faculty of engineering, ferdowsi university of mashhad, mashhad, iran. Mechanical properties of hydroxyapatite and ohcarbonated.
The spraying volume and the powder size directly influence the mechanical properties of the bone scaffold and the future biodegradation performance. To study the effect of mgo inclusion on the mechanical properties of pure hap, its composites with different 0. Oct 01, 2019 hydroxyapatite ha is a biologically active ceramic which promotes bone growth, but it suffers from relatively weak mechanical properties. Related content improving tribological and anticorrosion. In this paper we compute elastoplastic properties of hydroxyapatite single crystals from nanindentation data using a twostep algorithm. This study is focused on the role of nano hydroxyapatite particles on the mechanical properties of pmmaha nanocomposites. Laboratory for atomistic and molecular mechanics lamm, department of civil and environmental engineering, massachusetts institute of technology, 77.
The mechanical properties of polycrystalline hydroxyapatite are compared with those of cortical bone, dentine and enamel. However, the intrinsic brittleness and hardness of ha bulk materials. Carbonate hydroxyapatite and siliconsubstituted carbonate. In order to achieve a proper and homogeneous distribution of ha particles in the polymer matrix, mixer milling process was. Mechanical and thermal properties of hydroxyapatiteimpregnated bone cement intrusion into bone interstitial trabeculae is poor, and that prevents good mechanical coupling between the bone and the cement.
Mechanical and thermal properties of hydroxyapatite. The mechanical and microstructural properties, that is stiffnessstrength and porosity, of these mate rials see tables iii and iv will be used to. Carbon nanotube reinforced hydroxyapatite nanocomposites. Thus, in this study, a certain amount of low molecular weight pmma av. Mechanical properties of sintered hydroxyapatite for. Mechanical properties of some biomaterials and bone are summarized in table 1. This research synthesizes hydroxyapatitecalcium titanate compositeshactusing conventional route technique. Due to its outstanding properties such as biocompatibility, bioactivity, osteoconductivity and non toxicity and non inflammatory nature, nanohydroxyapatite bioceramic has got a variety of applications in medical and oral care areas. The alteration in mechanical properties of bone graft. Express 4 096409 view the article online for updates and enhancements. Hydroxyapatite interface zhao qin, alfonso gautieri, arun k. Collagenhydroxyapatite composites for hard tissue repair geiger et al. The effect of the ph values and sintering temperatures on the. To link to the entire object, paste this link in email, im or document to embed the entire object, paste this html in website to link to this page, paste this link in email, im or document.
A study on mechanical properties of pmmahydroxyapatite. When the size of powder is stable, the amount of binder spraying. Mechanical properties and cytocompatibility of biomimetic. In this way ha can be used for both trauma and elective joint replacement surgery. However, both materials have drawbacks in mechanical properties such as brittleness and low compressive strength. Effect of crosslinking on the mechanical properties of mineralized and nonmineralized. It is self evident that creating new tissue will lead to the best outcome for the patient in terms of quality of life and function of the surrounding tissue. It is observed that hydroxyapatite single crystals exhibit anisotropic mechanical response with a lower yield stress along the 1010. Singlecrystal hydroxyapatite and ohcarbonated hydroxyapatite have bending strength much higher than that of dense hydroxyapatite ceramic, indicating potential applicability to a loadbearing biomaterial.
Gics in dentistry due to their chemical and biological compatibility with human. Mechanical properties of hydroxyapatite composites reinforced. Mechanical properties of hydroxyapatite composites reinforced with hydroxyapatite whiskers. Mechanical, tribological, and biological properties of carbon. The mixing of bone and ha to form an aggregate will result in. Feb 23, 2001 generally speaking dense hydroxyapatite does not have the mechanical strength to enable it to succeed in long term load bearing applications. Biodegradable synthetic polymers have attracted much attention nowadays, and more and more researches have been done on biodegradable polymers due to their excellent mechanical properties, biocompatibility.
However, the big challenge regarding improving mechanical properties is maintaining bioactivity. In our study new biomaterial is created from deproteinised hydroxyaptite and endodentic cement, its mechanical properties were tested. Return to article details mechanical properties of glass reinforced hydroxyapatite download download pdf mechanical properties of glass reinforced hydroxyapatite. A study on mechanical properties of pmma hydroxyapatite nanocomposite. A study on mechanical properties of pmmahydroxyapatite nanocomposite seyed mojtaba zebarjad, seyed abdolkarim sajjadi, tahere ebrahimi sdrabadi, amir yaghmaei, behrooz naderi. Hydroxyapatite ha as a biomaterial can be used in human body because of its excellent osteo conduction, bioactivity, and biocompatibility with human tissues. The mechanical properties of a porous ceramic derived from a 30 nm 280 sized particle based powder of hydroxyapatite for potential hard tissue engineering applications sintered ceramics were also studied using xrd and fesem. Hydroxyapatite hap nanoceramic powder was synthesized successfully via microwave irradiation technique.
Home key engineering materials euro ceramics viii mechanical properties of. Hydroxyapatite ha is a biologically active ceramic which promotes bone growth, but it suffers from relatively weak mechanical properties. Wear, compression and threepoint bending tests were conducted. Nanomaterials free fulltext mechanical properties and. Carbon nanotube reinforced hydroxyapatite nanocomposites as. Mechanical properties of hydroxyapatite single crystals. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite sintered at a temperature of 0 c for 3 h were found to be 509, 1, 76 and 68 mpa, respectively. With a proper loading of nanoha in composites of 10 weight percent, the composites are also found with improved mechanical properties without catastrophic degradation. Impact of b2o3 and la2o3 addition on structural, mechanical and biological properties of hydroxyapatite sina khoshsima1, ammar z.
The mechanical properties of monoliths of calciumdeficient and carbonated hydroxyapatite formed by dissolutionprecipitation reactions at 38c have been determined. Mechanical and thermal properties of hydroxyapatite impregnated bone cement intrusion into bone interstitial trabeculae is poor, and that prevents good mechanical coupling between the bone and the cement. Mechanical properties of hydroxyapatite reinforced 45s5. The effect of incorporation of titanium oxide tio 2 and hydroxyapatite ha on the mechanical properties of wollastonite casio 3 was investigated in this. Coatings of hydroxyapatite are often applied to metallic implants most commonly titaniumtitanium alloys and stainless steels to alter the surface properties.
In order to achieve a proper and homogeneous distribution of ha particles. Pdf a study on mechanical properties of pmmahydroxyapatite. Natural hydroxyapatite and bone have similar physical and chemical characteristics make it biocompatible. To address this issue, we report fabrication of apatitebased composites by incorporation of alumina nanoparticles nal2o3. Study on the mechanical properties of threedimensional. Synthesis, properties and applications of hydroxyapatite. Calciumdeficient hydroxyapatite produced at a liquidtosolids ratio of 0. The present study aims to investigate the effect of short carbon fiber scfs and hydroxyapatite hap content on mechanical, tribological, and biological properties of high. Finite element evaluations of the mechanical properties of. Processing and tensile properties of hydroxyapatitewhiskerreinforced polyetheretherketone gabriel l. Pdf singlecrystal hydroxyapatite and ohcarbonated hydroxyapatite have bending strength much higher than that of dense hydroxyapatite ceramic.
Hydroxyapatite, also called hydroxylapatite ha, is a naturally occurring mineral form of calcium apatite with the formula ca 5 po 4 3 oh, but it is usually written ca 10 po 4 6 oh 2 to denote that the crystal unit cell comprises two entities. Pdf the main purpose of this study consists in investigating the direct microwave sintering of hydroxyapatite ha in a single mode cavity. Multiwalled carbon nanotubes mwcnts have high tensile strength and a degree of stiffness that can be used to. However, it has lower youngs modulus and fracture toughness with brittle nature. Thickness of hydroxyapatite nanocrystal controls mechanical.
In the first step the yield stress is obtained using hardness and youngs modulus data, followed by the computation of the flow parameters. Hydroxyapatite is the hydroxyl endmember of the complex apatite group. Pdf mechanical properties of hydroxyapatite and ohcarbonated. Hydroxyapatite hap is a calcium phosphate similar to the human hard tissues in morphology and composition. Facile synthesis of hydroxyapatite nanoparticles by a polymerassisted method. The aim of this research is to determine the effect of sintering i. Hence, habg composite has potential for enhance properties. Mechanical properties and microstructural behavior of hydroxyapatitetio2 electrospun nanofibers consolidated using high frequency induction heat sintering khalil abdelrazek khalil materials engineering and design department, high institute of energy, south valley university, aswan, egypt email. Mechanical properties and cytotoxicity of differently structured nanocellulosehydroxyapatite based composites for bone regeneration application by vijay h. However, the effects of carbonate on the strength are less clear. Hydroxyapatite, a naturally occurring form of calcium phosphate, is the main mineral component of bones and teeth. Microstructure evolution and mechanical properties. It is one of few materials that are classed as bioactive, meaning that it will support bone ingrowth and osseointegration when used in orthopaedic, dental and maxillofacial applications.
The mechanical properties of a porous ceramic derived from. Hydroxyapatite is used for bone reconstruction, in order to improve its mechanical properties different substances can be added. A study on mechanical properties of pmma hydroxyapatite nanocomposite seyed mojtaba zebarjad, seyed abdolkarim sajjadi, tahere ebrahimi sdrabadi, amir yaghmaei, behrooz naderi. Alshemary2, aysen tezcaner1,3, sedat surdem4, zafer evis1,3. This work focuses on the improvement of the mechanical properties of hydroxyapatite ha through the addition of 3 mol% yttria partially stabilized zirconia psz. Hydroxyapatite is chemically similar to the mineral component of bones and hard tissues in mammals. Fabrication, properties and applications of dense hydroxyapatite. Mechanical properties and cytocompatibility of biomimetic hydroxyapatite gelatin nanocomposites volume 21 issue 12 chingchang ko, michelle oyen, alison m. Additionally, higher mechanical properties such as youngs modulus of 119 gpa, high fracture toughness of 1.
Pdf mechanical properties of natural hydroxyapatite. May 30, 2014 the study revealed that the highest mechanical properties were found in stoichiometric ha samples sintered at 11001150c, having relative density of 99. Similarly, bioactive glass bg such as 45s5 has the ability to induce bone formation when exposed to physiological environment. The effect of titanium oxide and hydroxyapatite on the. This research synthesizes hydroxyapatitecalcium titanate composites hactusing conventional route technique. A handful of work focused on improving the intrinsic low mechanical properties of hydroxyapatite ha by various reinforcing agents. Paper open access effect of sintering on the mechanical. However, the poor mechanical properties of ha such as inherent brittleness, poor fatigue resistance, strength and particularly its low fracture toughness k. This study describes the effect of sintering temperature on the microstructural, calciumphosphorus cap ion ratios and mechanical properties of nonseparated biowastes processed hydroxyapatite. Phase, mechanical and bioactivity properties of hydroxyapatite. Therefore their mechanical properties are very important. Hydroxyapatite ha has been extensively studied for its exceptional ability in promoting osseointegration as in bone graft substitute and biomimetic coating of prosthetic implants. The current work aims to assess the effects of bg addition in ha system focusing on mechanical properties. Ha use is therefore typically limited to noncritical loadbearing applications, such as the ossicles.
The data obtained were used for studies of hap structures, the physical properties of hap density. In order to achieve a proper and homogeneous distribution of ha particles in the polymer matrix, mixer milling process was applied. It was observed that wear rate decreased by increasing in. Synthesis and enhanced mechanical properties of mgo. Hydroxyapatite ha has similar constituent with natural bone mineral and is able to evoke apatite formation on the bone interface.
Mechanical properties of hydroxyapatite composites reinforced with hydroxyapatite whiskers p. Eff ect of yttria addition on the microstructure and. Microstructure evolution and mechanical properties improvement in liquidphasesintered hydroxyapatite by laser sintering songlin duan 1,2, pei feng 2, chengde gao 2, tao xiao 3,4, kun yu 5, cijun shuai 2,3, and shuping peng 1,6, 1 hunan provincial tumor hospital and the affiliated tumor hospital of xiangya school of medicine. Thickness of hydroxyapatite nanocrystal controls mechanical properties of the collagen.
These values were about 8% and 14% of the total weight of the cement mixture, respectively. The calcium content of fish bone was analyzed by using atomic absorption spectroscopy. Generally speaking dense hydroxyapatite does not have the mechanical strength to enable it to succeed in long term load bearing applications. Despite its biocompatibility, the inherent mechanical properties of ha specifically brittleness, low tensile strength, and poor impact resistance have restricted its use in loadbearing applications 17. Ingole 1,2, tomaz vuherer 2, uros maver 3, aruna vinchurkar 4, anil v. Hydroxyapatite was synthesized from materials containing calcium. Mechanical properties and crystallization behavior of. For c1 samples, the content of ha in the total bone cement was 0.
Effect of deposition parameters and heattreatment on the. Hydroxyapatite ha, ca 10 po 4 6 oh 2, is the principal inorganic constituent of bone and teeth in vertebrates, and is the most stable calcium phosphate phase in physiological conditions. Mechanical, tribological, and biological properties of. In the threedimensional directly fabricating hydroxyapatite composite artificial bone scaffold process, the liquid biobinder is sprayed on the surface of bioceramics powder layer. Mechanical properties of yttriastabilized zirconia ceramics. The results provide quantitative relationships between pore geometry and mechanical properties of lattice scaffolds, and demonstrate that the hierarchical mechanical properties of natural oc tissue can be mimicked by tuning the porosity and local laydown angles in 3d printed scaffolds. Among them hydroxyapatite is most widely studied bioactive and biocompatible material. The present study investigates the chemical composition, solubility, and physical and mechanical properties of carbonate hydroxyapatite co 3 ap and siliconsubstituted carbonate hydroxyapatite sico 3 ap which have been prepared by a simple precipitation method. Facile synthesis of hydroxyapatite nanoparticles by a. Processing and tensile properties of hydroxyapatite.
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